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Department of Physics, Applied Physics, and Astronomy
Rensselaer Polytechnic Institute
110 Eighth Street, Troy, New York 12180-3590 USA

Telephone:
(518) 276-6310
Fax: (518) 276-6680
E-mail: physics@rpi.edu

Angel Garcia
Angel E. García

Department Head
Professor of Physics; Senior Constellation Chaired Professor in Biocomputation and Bioinformatics

Contact:

(518) 276-4206
angel@rpi.edu

http://origami.phys.rpi.edu

Education:

Ph.D., Theoretical Physics, Cornell University.
M.S., Physics, University of Puerto Rico, Rio Piedras
B.S., Physics (Magna cum Laude), University of Puerto Rico, Rio Piedras

Career Highlights:

García received a Ph.D. in Theoretical Physics from Cornell University . He is a fellow of the American Physical Society and a member of the Biophysical Society, The Protein Society, the AAAS, and the American Chemical Society.

He received the Edward Bouchard prize of the American Physical Society in 2006. García is an Associate Editor of Proteins, Structure, Function and Bioinformatics, a member of the editorial board of the Biophysical Journal, Molecular Simulations, and a member of the Faculty of 1000 for BioMed Central.

Research Interests:

Professor Garcia's research interests are theoretical and computational aspects of the structure, dynamics and stability of biological molecules.

Selected Publications:

1. N.G. Sgourakis, M. Merced-Serrano, C. Boutsidis, P. Drineas, Z. Du, C. Wang and A. E. Garcia, “Atomic-Level Characterization of the Ensemble of theAb(1–42) Monomer in Water Using Unbiased Molecular Dynamics Simulations and Spectral Algorithms” J Mol. Biol. 405: 570-583 (2011) DOI: 10.1016/j.jmb.2010.10.015

 2. D.R. Canchi and A.E. Garcia, “Backbone and Sidechain contributions in Protein Denaturation by Urea”, Biophysical Journal 100: 1526-1533 (2011)  DOI: 10.1016/j.bpj.2011.01.028

 3. A. Joshi, S. Kate, V.  Poon, D. Mondal, M. Boggara, A. Saraph, J. Martin, R. McAlpine, R. Day, A.E. Garcia, J. Mogridge, and R.S. Kane, “Structure-based Design of a  Heptavalent Anthrax Toxin Inhibitor” Biomacromolecules,  12: 791-796 (2011) DOI: 10.1021/bm101396u

 4. S. Vaitheesewaran and A.E. Garcia, “Protein Stability at a Carbon Nanotube Interface”, J. Chem. Phys. 134 :125101  (2011) DOI: 10.1063/1.3558776

 5. J-B. Rouget, Tural Aksel, J. Roche, J-L. Saldana, A. E. Garcia, D. Barrick, and C. A. Royer. “Size and Sequence and the Volume Change of Protein Folding”, J Amer. Chem. Soc.  133: 6020-6027 (2011) dx.doi.org/10.1021/ja200228w

 6. J. A Rodriguez and A. E. Garcia, " Concentration Dependence of NaCl ion distributions around DPPC lipid bilayers", Interdisciplinary Sciences-- Computational Life Sciences, Special Issue on "ionic fluids and their biological application". Interdiscip Sci Comput Life Sci 3: 1-11 (2011).  DOI: 10.1007/s12539-011-0107-4. Issue in Honor of Lesser Blum.

 7. J. Tian and A. E Garcia, “Simulations of The Confinement Of Ubiquitin In Self -Assembled Reverse Micelles”, J.Chem. Phys. 134: 225101 (2011)  DOI: 10.1063/1.3592712  (Issue Cover)

 8. C. Jimenez-Cruz, G. I. Makhatadze and A. E. Garcia, “Protonation/Deprotonation effects on the stability of the Trp-Cage Miniprotein”, ChemPhysChem, 13:17056-17063 (2011)  DOI: 10.1039/c1cp21193e (2011)

 9. Jianhui Tian and Angel E. Garcia, “Simulation studies of protein folding/unfolding equilibrium under polar and non-polar confinement”, J Amer. Chem. Soc.  133: 15157-15164 (2011) DOI: 10.1021/ja2054572

 10. D. Paschek, R. Day and A. E. Garcia, “Influence of water-protein hydrogen bonding on the stability of Trp-Cage miniprotein: A comparison between the TIP3P and TIP4P-Ew water models”. Phys Chem Chem Phys. 13: 19840-19847   DOI: 10.1039/c1cp22110h

Professional Appointments:

2005-present

 

Senior Constellation Professor for Biocomputation and Bioinformatics, Rensselaer Polytechnic Institute, Troy, NY

2001-2005

Group Leader, Theoretical Biology and Biophysics Group Theoretical Division, Los Alamos National Laboratory (LANL), Los Alamos, NM

1989-2005

Staff Member, Theoretical Biology and Biophysics Group, Theoretical Division, Los Alamos National Laboratory Los Alamos, NM

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